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At least four people died and dozens injured when a train crashed into a charter bus in the southern state of Mississippi, authorities said.

Police chief John Miller said at a news conference that the crash occurred yesterday at a railroad crossing in the Gulf Coast city of Biloxi.

Three people died at the scene and a fourth person died later, fire chief Joe Boney told the local Sun Herald newspaper.Of the 43 people on the bus, 35 were injured.