The 2 co-founders of Instagram have resigned, reportedly over differences in management policy with parent company Facebook.
The photo and video sharing service, founded in 2010, was bought by Facebook for one billion dollars in 2012. It now has more than a billion users worldwide.
Instagram announced on Monday that chief executive officer Kevin Systrom and chief technical officer Mike Krieger have stepped down, without giving an explanation.
US media reports say the 2 men may have been at odds with Facebook CEO Mark Zuckerberg over how to pursue profit while protecting privacy.
Facebook has seen a series of high-profile exits in recent months. A co-founder of the Facebook-owned messaging app WhatsApp resigned in April.